一、个人简介

刘立成博士，男，汉族，1983年4月出生，沈阳药科大学微生物与生化药学博士研究生，现任辽宁科技学院生物技术教研室专任教师。研究方向包括多肽类抗生素的设计、筛选、优化及其作用机制、抗菌肽表达载体的构建与优化、微生物发酵。

二、研究方向

多肽类抗生素的设计、筛选、优化及其作用机制、抗菌肽表达载体的构建与优化、微生物发酵。

三、研究成果（包括课题、专利、论文著作、科技奖励等）

（一）课题

辽宁科技学院校博士启动项目

（二）专利

无

（三）论文著作

1.Licheng Liu, Caiyun Wang, Mengyue Zhang, Zixuan Zhang, Yingying Wu and Yixuan Zhang*. An efficient evaluation system accelerates α-helical antimicrobial peptide discovery and its application to global human genome mining [J]. Frontiers in Microbiology, Accepted, DOI: 10.3389/fmicb.2022.870361.

2. Cai-Yun Wang,Li-Cheng Liu, Ying-Cai Wu, Yi-Xuan Zhang*. Identification and validation of four novel promoters for gene engineering with broad suitability across species [J]. Journal of Microbiology and Biotechnology, 2021, 31(8): 1154-1162.

3. Cai-Yun Wang, Ye Li, Zi-Wei Gao,Li-Cheng Liu, Meng-Yue Zhang, Tian-Yuan Zhang, Chun- Fu Wu, Yi-Xuan Zhang*. Establishing an innovative carbohydrate metabolic pathway for efficient production of 2-keto-L-gulonic acid in Ketogulonicigenium robustum initiated by intronic promoters [J]. Microbial Cell Factories, 2018, 17: 81.

4. Cai-Yun Wang, Ye Li, Zi-Wei Gao,Li-Cheng Liu, Ying-Cai Wu, Meng-Yue Zhang, Tian-Yuan Zhang, Yi-Xuan Zhang*. Reconstruction and analysis of carbon metabolic pathway of Ketogulonicigenium vulgare SPU B805 by genome and transcriptome [J]. Scientific Reports, 2018, 8: 17838.

5. Jin-Yan Xue, Meng-Yue Zhang, Yu Zhang, Juan Cheng,Li-Cheng Liu, Ying-Ying Wu, Tian- Yuan Zhang, Yi-Xuan Zhang*. Edaphovirga cremea gen. nov., sp. nov., isolated from the rhizospheric soil of Codonopsis clematidea [J]. Journal of Microbiology, 2019, 57: 337–342.